JJAP Conference Proceedings

JJAP Conf. Proc. 4, 011110 (2016) doi:10.7567/JJAPCP.4.011110

A flicking method for generation of polymer microbeads

Chin Fhong Soon1,2, Soon Chuan Wong1, Wai Yean Leong1, Mohd Khairul Ahamd, Kian Sek Tee1

  1. 1Faculty of Electrical and Electronic Engineering, Universiti Tun Hussein Onn Malaysia, 86400 Parit Raja, Batu Pahat, Johor, Malaysia
  2. 2Biosensor and Bioengineering Laboratory, MiNT-SRC, Universiti Tun Hussein Onn Malaysia, 86400 Parit Raja, Batu Pahat, Johor, Malaysia
  • Received September 23, 2015
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Abstract

A variety of microencapsulation technology has been developed to encapsulate drugs, cells and food. However, previous microencapsulation systems were associated with complex design, requirements of high voltage supply, post cleaning process and consuming large volume of reagents. This work proposed a simple yet efficient flicking system for the production of calcium alginate microbeads. In the system, a flicking device was designed to disperse microdroplets of sodium alginate ejecting from a syringe pump and the microbeads were polymerised in the calcium chloride solution. The size of the microbeads produced using this system can be controlled by changing the flow rate (5, 10, and 15 µl/min) of the syringe pump and fixing the motor rotation speed of the flicking device at 90 rpm. The microbeads of calcium alginate produced using the flicking device were shown to be size controllable in a range of 270 to 430 µm and they have potential for the microencapsulation of cells.

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